SL OMFX

  Answer : Warthin tumour Second most common tumour of salivary gland 5-15% of all cases 6 th and 7 th decades Male > Female Linked to cigarette smoking Table 6 Histopathology Papillary projections lined by epithelium Lymphoid stroma Papillary cystic structures lined by epithelium Epithelium Inner – Columnar Outher - Cuboidal With germinal centers  After FNAC – necrosis confused with malignancy  Granulomatous reaction with langerhan type giant cells may seen Oncocytes – epithelial cells characterized by excessive number of mitochondria When present in a lower pole metastatic node is a suspicion  May associate with HIV (P 27 positivity in HIV) Technetium 99 may appear as hot lesion Complete surgical excision with adequate margin  Parotid resection nomenclature Anatomical Functional Extracapsular dissection Partical parotidectomy Superficial parotidectomy Deep parotidectomy Conservative Semi conservative Radical Eg : Conservative superficial parotidectomy D...

  Answer : Oral lichen planus Varying degrees of orthokeratosis and parakeratosis may be present on the surface of the epithelium The thickness of the spinous layer can also vary.  The rete  ridges may be absent or hyperplastic, but they classically have a pointed or “saw-toothed” shape Destruction of the basal cell layer of the epithelium  (hydropic degeneration) is also evident.  This is accompanied  by an intense, bandlike infiltrate of predominantly T lymphocytes immediately subjacent to the epithelium Degenerating keratinocytes may be seen in the area of the epithelium and connective tissue interface and have been termed colloid, cytoid, hyaline, or Civatte bodies. Download the Oral Pathology Short cases clicking the following link Click Here

  Answer : Pleomorphic adenoma The most common salivary gland tumour 2-3.5 cases / 100,000 Occurs in all ages Most common 3-6 th decades Female : Male = 2 : 1 Parotid >Palate>Submandibular  Usually solitary but synchronous or metachronus lesions may occus Major glands – encapsulated Minor glands – non encapsulated  Histopathology Main diagnostic Duct like structures and + mucin casts  Epithelial component Stroma  Ductal epithelial cells – 2 layered inner squamous and outer cuboidal Duct like Strands Islands Myxoid Mucoid Myoepithelial cells- produce stroma Spindle Plasmacytoid Ovoid Epitheliod Chondroid – similar to hyaline cartilage  Osseous  Squamous metaplasia and keratin pearls may not be unusual Mutation – PLAG1 Hyalinization and very dense collagenation – Very high chance of malignancy Types of malignancy arising from PA Ca. Ex – pleomorphic adenoma (Adeno ca, duct ca, myoepithelial ca) Carcino sarcoma Metastasizing PA – Histologically ...